In 1991, Disney's Touchstone Pictures had a potentially big project on its hands- Sister Act! Of course such a project required one of Disney's biggest contract stars of that time to appear in it- Bette Midler.
Yes, Bette Midler was the original Delores Van Cartier- a lounge singer who finds herself in the wrong place at the wrong time. Ms. Midler, for reasons known only to herself, chose to bow out of the film at the last minute and so the studio had to scramble to find someone else. Of course, their second choice was obviously...... Dolly Parton? Unfortunately, Ms. Parton was unable to fit the film into her schedule, so the search continued. Finally they got a yes. The new star of the movie would be Whoopi Goldberg. The film would go on to be a colossal hit, spawning a hit soundtrack, sequel and Broadway musical. Perhaps Ms. Midler grew to regret her decision.