Sally from Nightmare Before Christmas is an unusual character. Despite the fact that she is depicted as a sympathetic character, she is constantly trying to poison her creator, Doctor Finklestein.
While the doctor is a bit overbearing and demands much of Sally's time, he's not shown to be someone deserving of nightly poisonings. Yet we do feel sorry for Miss Sally, who longs to do as she pleases, which mostly revolves around walks with Jack Skellington.
Sally's voice is provided by the legendary comedienne Catherine O'Hara who both speaks and sings for Sally.